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Understanding Your
Skin & Free Radicals
Skin is the protector
of the human body.
Our skin -"cutaneous envelope" - contains us and protects
us from the outside world.
Skin is the largest organ of
the body, requiring proper care to maintain its optimum healthy
balance. It is extremely important for skin to receive constant
nourishment of minerals and vitamins and to maintain a slight
acidic low pH balance to remain healthy.
Soaps, cleansers, poor diet,
and exposure to the many stresses of our environment are very
harsh on the skin creating interference with the delicate balance
nature intended. This imbalance of our protective barrier provides
the perfect breeding ground for bacteria, many times resulting
in many types of skin irritations while also accelerating the
aging process by creating an excess of free radicals, causing
cellular breakdown.
The structure of the skin is divided into three main layers:
1. Epidermis 
- Highly cellular uppermost layer.
- 50%-70% moisture content.
- Subdivided into layers.
a. (Stratum Corneum) outermost layer where cells are continually
shed.
b. (Basal Layer) deepest layer where skin cell renewal occurs.
2. Dermis
- Largely fibrous and elastic support layer of the skin.
- Contains many important structures:
a. (Collagen) provides strength and allows the skin to stretch
and contract.
b. (Elastin) gives the skin elasticity.
c. (Hair follicles) provide an entry for moisture and exit or
excess oils.
d. (Oil glands) produce sebum, the skins natural oil.
e. (Sweat glands) keep the skin naturally moist and excrete toxins.
3. Subcutaneous Layer
- Bottom-most layer of skin.
- Gives smoothness and contour of the body
- Contains fats or uses as energy.
- Function as a cushion for the outer layers of the skin and
protect vital internal organs.
- Contributes essential materials for growth, nourishment and
repair of the skin.
What are Free Radicals?
Free radicals are atoms
or molecules that have one or more unpaired electron(s), and
are therefore unstable. These highly reactive atoms can damage
molecules in the cell membrane as electrons are taken from healthy
cells. One free radical can initiate literally tens of thousands
of reactions. The chain reaction that is set off is extremely
damaging to the body. Free radicals cause cancer, diabetes, cataracts,
cardiovascular disease, collagen deterioration, premature aging,
wrinkling, age spots, discoloration to the skin, and many other
illnesses. It is now universally accepted in medical and scientific
circles that oxidative damage to cell components is one of the
foremost causative factors for major diseases having a profound
negative effect on the aging process.
We are exposed to free radicals from the air we breath, sunlight,
active or passive cigarette smoke, car fumes, industrial pollution,
food that we eat and everyday activities. It is virtually impossible
to escape exposure from free radicals and our bodies are unable
to protect themselves.
How Vitamin C Solution
in 20 micron particles Helps Fight Free Radicals
Volatile, or unstable free
radicals consist of molecules that speed aging by destroying
collagen, the glue-like substances that, along with firming strands
called elastin, make skin resilient, firm, and less prone to
wrinkles. As
the free radicals become neutralized with antioxidants, like
those found in the form of REVENIR's highly energized Vitamin
C, skin remains more plump and elastic.
Unlike creams formulated with
Retin A and AHAs, which work by exfoliating the older, outer
skin layers, REVENIR's energized Vitamin C works within the skin
layers, inhibiting the production of free radicals and spurring
the synthesis of collagen. Working at this cellular level, Vitamin C helps
"reweave" the skin fibers. As cells bind together, skin looks
more smooth and youthful.
Vitamin C has been clinically
proven to:
- Promote collagen synthesis
- Be a major anti-oxidant
- Act as an anti-inflammatory
- Inhibit the enzyme tyrosinase
(in certain Vitamin C derivatives)
Collagen is responsible for
providing suppleness and elasticity in the skin. As we age, the
level of collagen in the skin is reduced. Collagen and elastin
fibres stiffen and break apart, forming an unstructured mass.
In turn, wrinkles are formed. For years, moisturizers have contained
collagen and elastin. But, the collagen and elastin must be produced
as part of the living cell. Delivering Vitamin C to the stratum
basale level where new live cells are produced is the only way
to improve the availability of collagen. Studies have proven
that topically applied Vitamin C can improve the production of
collagen. Massaging creams with collagen and elastin are not
able to accomplish this.
Not all Vitamin C derivatives
are created equal.
After studying a variety of derivatives, it was found that certain
types of Vitamin C derivatives inhibited the enzyme tyrosinase,
allowing them to act as whitening agents. Tyrosinase is a rate
regulating enzyme, responsible for the production of melanin.
Typical tyrosinase inhibitors are hydroquinone and kojic acid.
Ascorbic acid, ascorbyl glucoseamine and ascorbi-cell report
the ability to inhibit tyrosinase, in turn, making these types
of Vitamin C a better alternative to hydroquinone and kojic acid.
Magnesium ascorbyl phosphate and ascorbyl palmitate were reported
to have no effect on tyrosinase, and in turn were predicted to
not have any effect on melanin synthesis.
The key to topically applied
vitamin C is the availability of effective L-ascorbic acid. Ascorbic
acid is extremely unstable in the presence of light and oxygen.
It is normal for a Vitamin C formulation to have a light, natural
tan color. But, as the ascorbic acid deteriorates, it continues
to turn dark brown and becomes less effective or even ineffective.
Some quick to join the ranks with Vitamin C products have added
only small amounts of ascorbic acid or a derivative to the product,
allowing for a reference to "Vitamin C" on the packaging.
Others are turning to other forms or derivatives, such as magnesium
ascorbyl phosphate, ascorbyl palmitate, ascorbyl stearate, ascorbosilane,
Ascorbyl Glucoseamine, Sun Caps-C, ascorbic acid sulphate, Stableact
C Plus, Ascorbi-Cell. When each of these forms is utilized, the
active must be converted to L-ascorbic acid in high enough concentrations
to be effective.
The greatest hurdle inherent
to Vitamin C skin application is its volatile chemical structure.
On contact with oxygen, Vitamin C becomes completely inert. A
wide variety of delivery systems have been attempted from microcapsules
to microsponges. None have proven to be completely efficient
and research is still being done to maximize the anti-oxidant
capabilities of Vitamin C in skin care. REVENIR was developed from years of
scientific research and technological advances. It is the most
efficient delivery method for transporting Vitamin C to the dermis
level of the skin today. |
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